Yale researchers have created "Ochre," a genomically recoded organism that enables the production of synthetic proteins with ...

Here, the authors show that the Reh1 is positioned in the polypeptide exit tunnel of 80S ribosomes, suggesting that the growing polypeptide chain displaces Reh1 during first round of translation.

RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is read by ribosomes to generate protein (translation). Biologically active RNAs ...

In frame translation initiation sites within coding sequences drive the expression of N-terminally truncated proteoforms.